Web3 Nov 2014 · Ferritin made up of only FHC can circulate and bind specifically and saturably to various cell types. Using expression cloning and protein interaction assays, Li et al. … Web2 days ago · TfR1 interacts with Fe-TF to transport iron into the cell, storing it as a ferritin complex. Subsequently, NCOA4 directly binds FTH1 of the ferritin complex and is transported to an autophagosome. This binds to LC3 and is then transported to the autolysosome, where the ferritin complex is degraded to release iron.
(A) qRT-PCR analysis of FPN, HAMP, HFE, TFR1, FTH1, FTL and …
Web19 May 2024 · BACKGROUND Serum ferritin is a useful tumor marker for renal cell carcinoma (RCC). However, the expression of ferritin heavy chain (FTH1), the main … WebC, Immunoblot analyses of FTH1, NCOA4, FBXL5, IRP2, TfR1, tubulin, and laminB1 in WT and NCOA4 C410A HEK293T cells (clone #2) treated with 25 μg/ml FAC for the indicated times. Soluble and insoluble lysates were subjected to SDS-PAGE and analyzed by immunoblotting with the indicated antibodies. The asterisk indicates non-specific bands. prof. dr. orawon chailapakul
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Web11 Mar 2024 · Glutathione peroxidase 4 (GPX4) utilizes glutathione (GSH) to detoxify lipid peroxidation and plays an essential role in inhibiting ferroptosis. As a selenoprotein, … WebThe iron regulatory protein 1/2 (IRP1/2) can bind to the iron responsive element (IRE) to regulate the expression of various iron metabolism proteins (DMT1, TFRC, FPN, … WebWe investigate the distribution and biological effects of polyethylene glycol (PEG)-coated magnetite (Fe3O4@PEG) nanoparticles (~30 nm core size, ~51 nm hydrodynamic size, 2 mg Fe/kg/day, intravenously, for two days) in the aorta and liver of Wistar–Kyoto (WKY) and spontaneously hypertensive rats (SHR). Fe3O4@PEG had no effect on open-field … religious macrame