WebRoman Manetsch – CV (01/20/2024) – page 1 ... Faculty Fellow, Center for Drug Discovery Northeastern University 102 Hurtig Hall, 360 Huntington Avenue, Boston, MA 02115 (USA), Phone: 617-373-6316, E-mail: [email protected] webpage: www.manetschlab.com EDUCATION / EMPLOYMENT HISTORY WebJun 23, 2024 · We show this compound works rapidly in vivo with a half-life of ~3 days. The efficacy, low toxicity, and pharmacodynamics of cross-linker mediated stabilization make it a promising therapeutic approach for SOD1-related fALS. Significance statement Cyclic thiosulfinate S -XL6 enables the kinetic stabilization of ALS-associated SOD1 variants, in ...
Benoît Witkowski Institut Pasteur du Cambodge Phnom Penh …
WebDec 5, 2024 · Roman Manetsch Northeastern University Boston, MA 1 protocol Chester Joyner University of Georgia Athens, GA 1 protocol ... Nathan M. Chasen, Wayne T. Cheng, Chester J. Joyner, Roman Manetsch, Benoît Witkowski and Dennis Kyle, date: 12/05/2024, view: 1777, Q&A: 0. WebJan 24, 2024 · He moved to Northeastern in the fall of 2010. He is an author of over 100 scientific research papers and numerous review articles on innovative analyses of biophysical data with focus on x-ray and neutron scattering and x-ray imaging. Education PhD, Massachusetts Institute of Technology, 1976 Honors & Awards cojean parvis
Lab Members The O.R.G. - Northeastern University
WebPresent address: Department of Chemistry and Chemical Biology, Department of Pharmaceutical Sciences, Northeastern University360 Huntington Avenue, Boston, MA 02115-5000, USA. E-mail: [email protected], www.manetschlab.com WebJul 20, 2024 · Roman Manetsch Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA; Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA Correspondence [email protected] View further author information. Pages 626-631 WebWe work closely with medicinal chemistry groups (George O’Doherty and Roman Manetsch, Northeastern University) and the structural biology group of Ed Yu (Case Western Reserve University Medical Center) inclusive of cross-mentorship of postdoctoral fellows and combined lab group meetings for our collaborative projects. cojean prix