WebOne type, linear morphea, tends to develop before 18 years of age. The other types are most likely to begin between the ages of 30 and 50. ... We also know that a person develops scleroderma when the body makes too much collagen. This excess collagen is what causes the skin to thicken and harden. It can also cause hardening and thickening in ...
Scleroderma - Symptoms and causes - Mayo Clinic
WebAug 25, 2024 · Departments and specialties. Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. WebJan 25, 2024 · Morphea is characterized by initial inflammation followed by fibrosis of the skin and soft tissue. Despite its substantial morbidity, the pathogenesis of morphea is poorly studied. ... For collagen mRNA assays, 50–100 ng/ml recombinant mouse CXCL9 or CXCL10 (R&D Systems) or vehicle control (PBS) were added to wild-type fibroblasts for … st gobain melton mowbray
Morphea - an overview ScienceDirect Topics
WebFeb 20, 2024 · Morphea, also called localized scleroderma, is a rare inflammatory skin condition that can also affect the subcutaneous tissues. Morphea encompasses multiple variants with different outcomes ranging … WebAug 25, 2024 · Diagnosis. Your doctor may diagnose morphea by examining the affected skin and asking about your signs and symptoms. Your doctor might also take a small … Mayo Clinic Q and A: Treating a rare skin disorder known as morphea Sept. 30, … Morphea is most common in white females. Age. The condition can affect people at … WebApr 11, 2024 · Morphea -Morphea, also known as localized scleroderma, is an inflammatory condition characterized by increased collagen accumulation in the skin and subcutaneous tissues. Generally, the morphea skin changes appear on the abdomen, chest, or back of the body, but they can also appear on the face, arms, or legs. st gobain malvern pa